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ACTH-derived peptide for neuroprotection and cognitive research.
SKU: SMX-10MG
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Semax is a synthetic peptide researched for its effects on neuroprotection and cognitive function, shipped same business day from Melbourne with free express shipping on orders over $200.
Semax is derived from a fragment of adrenocorticotropic hormone (ACTH), engineered to retain the cognitive and neuroprotective effects of ACTH while eliminating its hormonal activity. Semax has been extensively studied for over 30 years and is widely regarded as one of the most well-documented nootropic peptides.
Semax is listed on Russia's List of Vital & Essential Drugs and has been approved there for the treatment of stroke, cognitive disorders, optic nerve disease, and as a general nootropic. It has demonstrated an excellent safety profile with no reported tolerance, dependence, or withdrawal, even with extended use.
Semax enhances cognitive function and neuroprotection through multiple neurotransmitter and neurotrophic pathways:
| Mechanism | Action | Biological Effect |
|---|---|---|
| BDNF/NGF Upregulation | Rapidly elevates neurotrophic factors in hippocampus and cortex | Neuroplasticity, memory consolidation, neuronal survival |
| Dopamine Activation | Stimulates dopaminergic brain systems | Focus, motivation, and cognitive drive |
| Serotonin Modulation | Enhances serotonin metabolism in the brain stem | Mood stabilization and stress resilience |
| Enkephalin Protection | Inhibits enkephalin-degrading enzymes | Pain modulation and endogenous peptide preservation |
Where Selank (its sister peptide from the same research program) is primarily an anxiolytic that works through GABA modulation, Semax is primarily a nootropic and neuroprotectant that works through BDNF upregulation and monoamine activation, making them complementary rather than interchangeable.
Semax is being studied for its potential effects on:
In a clinical trial with 110 stroke patients, intranasal Semax increased plasma BDNF levels and led to improved motor performance and functional independence. In healthy subjects, a single dose improved memory test accuracy from 41% to 71% compared to controls.
There are many research peptide suppliers in Australia. Here's what sets us apart:
FOR RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. This product is intended for laboratory and research purposes only. Not for human or animal consumption.
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Complete reusable peptide pen kit for precise research dosing.
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