SS-31

Buy SS-31 online from Research Chems Australia

SS-31 is a mitochondria-targeting peptide studied for cellular energy optimisation and oxidative stress reduction, shipped same business day from Melbourne with free express shipping on orders over $200.

What Is SS-31?

SS-31 is a first-in-class compound that directly addresses mitochondrial dysfunction. Unlike conventional antioxidants that work systemically, SS-31 concentrates 5,000-fold within mitochondria, directly addressing dysfunction at its structural source.

With multiple clinical trials completed or ongoing across heart failure, mitochondrial myopathy, Barth syndrome, and age-related muscle decline, SS-31 is among the most clinically advanced mitochondria-targeting peptides in development.

How Does SS-31 Work?

SS-31's selective interaction with cardiolipin influences mitochondrial structure and function:

Unlike conventional antioxidants that scavenge free radicals systemically, SS-31's cardiolipin binding addresses mitochondrial dysfunction at its structural source by stabilizing the membrane architecture required for efficient electron transport.

Research Focus Areas

SS-31 is being studied for its potential effects on:

• Heart failure — left ventricular function and cardiac remodeling
• Primary mitochondrial myopathy — muscle function restoration
• Barth syndrome — cardiolipin metabolism disorders
• Ischemia-reperfusion injury — cardiac and renal protection
• Aging muscle — sarcopenia and exercise tolerance
• Neurodegenerative diseases — Alzheimer's and Parkinson's models
• Diabetic complications — nephropathy and cardiomyopathy
• Optic neuropathy — Leber's hereditary optic neuropathy

Phase 2/3 trials have shown mixed efficacy results across indications, with a consistently favorable safety profile.