GHK-Cu Starter Kit

Kit Contents:

• 100mg GHK-Cu
• 10ml Bacteriostatic water
• 1x 18G Reconstituion syringe
• 5x 29G Insulin syringes
• 6x Alcohol swabs

The Regenerative Copper Peptide

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring tripeptide-copper complex first isolated from human plasma in 1973 by Dr. Loren Pickart. This small peptide demonstrates a remarkably broad spectrum of regenerative activities, from wound healing and skin rejuvenation to gene expression modulation affecting over 4,000 human genes.

With plasma levels declining from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60, GHK-Cu has attracted significant attention in anti-aging and regenerative medicine research.

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Why Copper Chelation Matters

GHK's high-affinity binding to copper(II) ions creates a bioactive complex:

Property	Function	Biological Effect
Copper Delivery	Modulates cellular copper uptake	Essential enzyme activation
Gene Modulation	Affects 4,000+ genes	Broad regenerative signaling
MMP Regulation	Balances matrix turnover	Tissue remodeling
Antioxidant	Reduces oxidative stress	Cellular protection

The tripeptide's ability to deliver copper while simultaneously modulating gene expression distinguishes it from simple copper supplementation.

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Research Focus Areas

GHK-Cu is being studied for its potential effects on:

• Skin regeneration — collagen, elastin, and glycosaminoglycan synthesis
• Wound healing — accelerated closure and reduced scarring
• Anti-aging — reversal of age-related gene expression patterns
• Hair follicle stimulation — promotion of hair growth in preclinical models
• Antioxidant protection — cellular defense against oxidative damage
• Anti-inflammatory action — reduction of pro-inflammatory cytokines
• Tissue remodeling — balanced MMP/TIMP regulation
• Neuroprotection — potential CNS regenerative effects

Clinical studies have demonstrated improvements in skin thickness, elasticity, and appearance with topical application.

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Clinical Development Context

• Discovery: 1973 (Dr. Loren Pickart)
• Phase: Extensively studied; used in cosmetic products
• Clinical data: Multiple human studies for skin applications
• Regulatory status: Widely used in cosmetics; not FDA approved as therapeutic

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Technical Specifications

• Synonyms: Copper tripeptide-1, Copper peptide GHK
• Class: Copper-binding tripeptide / Regenerative peptide
• Sequence: Glycyl-L-Histidyl-L-Lysine
• Molecular Formula: C₁₄H₂₄N₆O₄Cu (as copper complex)
• Molecular Weight: ~403.9 g/mol (copper complex)
• Form: Sterile lyophilized powder or solution
• Natural occurrence: Plasma, saliva, urine

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Storage & Handling

• Lyophilized: Store at -20°C
• Reconstituted: Store at 2–8°C
• Protect from light and moisture
• pH-sensitive; maintain appropriate solution conditions

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